There aren't any enough research that assess effects of modafinil in pregnant women. Intrauterine development retardation and spontaneous abortion have been reported.
Other medication, such as ketoconazole and itraconazole could cut back the effectiveness of modafinil. Some other medication which will increase the effectiveness and/or toxicity of modafinil. These medicine embody carbamazepine , phenobarbital, and rifampin .
The mixture of therapy with CPAP and modafinil could also be essential to greatest deal with your condition. If you take modafinil to treat sleepiness brought on by obstructive sleep apnea, you might also be treated with a steady optimistic airway strain machine. This machine is an air pump connected to a mask that lightly blows pressurized air into your nose whilst you sleep. The pump doesn't breathe for you, however the gentle drive of air helps hold your airway open to prevent obstruction. Modafinil is normally taken every morning to stop daytime sleepiness, or 1 hour earlier than the beginning of a work shift to treat work-time sleep issues.
Because multi-organ hypersensitivity is variable in its expression, different organ system symptoms and indicators, not famous right here, might happen. Although benign rashes additionally happen with modafinil, it is not potential to reliably predict which rashes will prove to be severe. Accordingly, modafinil ought to ordinarily be discontinued on the first sign of rash, until the rash is clearly not drug-associated. Discontinuation of therapy could not stop a rash from turning into life-threatening or permanently disabling or disfiguring. The adverse reaction profile was similar throughout these studies. The recommended dosage of PROVIGIL for sufferers with SWD is 200 mg taken orally once a day as a single dose roughly 1 hour previous to the beginning of their work shift.
The 400 mg dose will not be simpler than the 200 mg dose. Call your physician when you proceed to have excessive sleepiness even while taking modafinil. Do not stop using your CPAP machine throughout sleep until your physician tells you to.
Never share modafinil with another particular person, especially somebody with a historical past of drug abuse or habit. Keep the medication in a place the place others can not get to it. Modafinil is used to treat extreme sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Do not take medications containing armodafinil while utilizing modafinil.
The beneficial dose is 200 mg once every day to not exceed 400 mg. It ought to be administered within the morning for treating narcolepsy or obstructive sleep apnea, and one hour previous to work in those with shift work disorder.